Samuel Stavis

A Multifunctional Microstructure for Microscope Calibration and Nanoparticle Characterization

K.T. Liao, C. R. Copeland(*), J. H. Myung, D. Kozak, S. M. Stavis(*), Food and Drug Administration, (*)National Institute of Standards and Technology

We integrate micropillar arrays into microfluidic slits to improve the accuracy of nanoparticle tracking and sizing. The pillar height sets the slit depth and the array pitch enables microscope calibration. These complementary functions yield a microscopic focal volume that is under control and that has traceable dimensions.