Mark Schvartzman
Ben-Gurion University of the Negev
Micro-/Nano-scale Platforms for the Controlled Ex-vivo Mechano-Stimulation of Cells
We engineered micro/-nano- engineered platforms for cell stimulation of lymphocyte activation. The platforms were based on nanoimprinted molecular patterns of signaling ligands and mechanoresponsive nanowires. We also engineered micropatterns with varied stiffness and used them to reveal a new mechanism of cell mechano-sensing.
About Mark Schvartzman
Mark Schvartzman is an Associate Professor in the Department of Materials Engineering at Ben-Gurion University of the Negev, Israel. His research focuses on the design of novel nanomaterial and nanofabrication approaches for three main applications. The first one is biomimetic nanoscale devices for the mechanical stimulation of cytotoxic lymphocytes, aimed at understanding the biophysical mechanism of the immune activation of these cells by their natural environment. The second one is a micro-engineered platform for the modulation of cytotoxic lymphocytes for anti-cancer immunotherapy. Finally, the third one is subwavelength structures for optical applications on unconventional optical materials. Mark Schvartzman received M.Sc. and B.Sc. in Chemical Engineering from Technion – Israel Institute of Technology and a Ph.D. in Chemical Engineering from Columbia University. Before joining Ben-Gurion University in 2014, he did postdoc training at the Weizmann Institute of Science.
